Python is a general purpose interpreted programming language with great code readability and very beginner-friendly.
CMS or Content Management System enable users to manage websites without needing to know to many technical details. Python based CMS's are not as widespread as some of its counterparts, however boast some benefits over other content management systems.
There are a lot of Python-based CMS's each with its unique benefits. There are Zope-based Python solutions (Z Object Publishing Enviroment) like Plone, Nuxeo CPS, Silva as well as non-Zope based like Django, ikaaro, Kotti and others. Depending on the main purpose of your project, each of these CMS's will deliver certain advantages. Read the reviews, ask questions and share your own pros and cons of Python CMS.